2nd July 2009 Technical Newsletter
July 2009 Fluorous Technical Newsletter
CEOverture
Communication is at the core of effective relationships, be they personal or business. Whether you connect with us through our website, blog, or newsletter, our goal is to bring you the information you want and need. Of course, direct communication is even more effective, so e-mails, phone calls and live-and-in-person discussions are especially valued. I see an opportunity for a little bit of all of these means of communication in this edition of our Technical Newsletter, and I hope you’ll find the one best suited for your needs. Thank you giving us the opportunity to communicate with you.
Cheers,
Philip E. Yeske
President & CEO
Fluorous Technologies Inc.
Fluorous Posters from ASMS
In case you missed ASMS, two fluorous posters from the conference are now available for viewing via the links below. Each of these uses fluorous tags and FSPE to enrich samples in specific peptide subsets for proteomics studies. Visit our proteomics page to learn how we can provide you with the reagents and separation media you need to incorporate fluorous separations into your research.
- On-Substrate Labeling of Peptides Using Cleavable Fluorous Labels Immobilized on Fluorous Silica Support
- Protein/Peptide Labeling Using Novel Acid-Cleavable Fluorous Affinity Tags
These posters will be archived in our presentations page. We encourage you to submit your fluorous posters or presentations to us for inclusion on our website.
Fluorous Immobilization via Click Chemistry
The immobilization of fluorous molecules onto a fluorous modified surface has been conducted on various molecular classes including peptides, carbohydrates, and small molecules to form microarrays. In nearly all of these cases, fluorous tags are attached to the probe molecules before they are spotted onto the surface. A recent report from Chengzai Cai’s group at the University of Houston provides an alternative method for the fluorous immobilization of probes. The researchers first immobilized a fluorous alkyne on a fluorous modified glass slide and then spotted a solution containing a copper catalyst and a probe molecule with a tethered azide. Click chemistry attached the probe to the immobilized fluorous alkyne to create the microarray. The Cai group also demonstrated click chemistry using an immobilized fluorous azide with alkyne tethered probes. To read more about this work and its implications please see the F-Blog entry.
F-Blog is one of the best ways to interact with the fluorous literature and research community. Please join us by contributing your comments and feedback to the only blog dedicated to all things fluorous.
ISoFT’09
The full technical program for the International Symposium on Fluorous Technologies (ISoFT’09) to be held at Jackson Hole, WY from Aug 23-28th is now available. This conference, being held in conjunction with the International Symposium on Fluorine Chemistry (ISFC), will consist of nearly 300 oral presentations and posters. Four oral sessions and one poster session will be completely dedicated to fluorous chemistry, although many presentations using fluorous chemistry will also be at given at other sessions. To view the full technical schedule please click here, then click on any of the ISoFT’09 sessions to view the abstracts. ISFC/ISoFT’09 will provide attendees with the best opportunity to meet all the leading researchers in the field and to learn the latest in fluorous chemistry. Whether you’re making small molecule libraries, synthesizing biomolecules, or forming fluorous microarrays, ISoFT’09 is the place to be.
If you are attending the conference and would like to meet with a representative from Fluorous Technologies Inc. please contact us.
If you are unable to attend the conference, you will be able to follow the events on F-Blog.
To learn more about this exciting conference including registration information, please visit the ISFC/ISoFT’09 website.
The New Fluorous Technical Newsletter RSS Feed
It is now possible for you to use our new RSS feed to receive the Fluorous Technical Newsletter. The feed, powered by Google’s Feedburner service, offers you a wide array of reading choices. Add it to your favorite RSS reader, or have an emailed version of the Newsletter sent to your in-box.
We believe that the interface is much easier to use and understand than our current system, and we’d like to migrate our entire mailing list over to the RSS feed by the end of the year. More details to come as we develop our plans. For now, we’ll continue to send out the newsletter in our traditional manner as we test the RSS feed possibilities.
Summer Promotion
Summertime and the living is easy as the song goes. Summer is a great time for researchers to try new things, to start new projects, and to explore new techniques. As an incentive to incorporate fluorous techniques into your research Fluorous Technologies is offering a special 20% summer discount on any order over $250 from first time customers or customers who haven’t ordered from us in over a year. Just place your order before Sept 21st and refer to the discount code SUM20.
The Fine Print
Fluorous Technologies is a chemical technology company devoted to the development and commercialization of fluorous products for the life science market. The company uses its patented technology to solve synthesis and separation problems spanning the entire drug discovery and development process. Fluorous chemistry enhances a wide range of applications, including medicinal chemistry, combinatorial chemistry, catalysis, peptide and oligonucleotide production, and proteomics. For more information, please visit: http://fluorous.com
For questions, quotes, orders, product availability, and access to technical resources, please email us or call 412-826-3050.
Fluorous Technologies Inc. is located at 970 William Pitt Way, Pittsburgh, PA 15238 USA.
FluoroFlash® is a registered trademark of Fluorous Technologies Inc.