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HPLC Columns   

SPE Cartridges  

SPE Plates

FluoroFlash® NuTips  

Fluorous Silica Gel   

TLC Plates

Fluorous Modified Glass Slides

LC Trap Cartridges


The separation of fluorous compounds from non-fluorous compounds using FluoroFlash® silica gel is the central theme of fluorous techniques.  Under the appropriate conditions the FluoroFlash® stationary phase retains the fluorous compounds with exceptional efficiency and selectivity.  A simple switch of the mobile phase then effects release of the fluorous compounds from the stationary phase.  FluoroFlash® silica gel is characterized by its high loading capacity, outstanding selectivity, and easy recyclability (1-2).


FluoroFlash® silica gel is available in a vareity of formats from analytical to preparative and from pre-packaged to loose bulk.  FTI can also custom format FluoroFlash® silica to meet your purification needs.  Just click on the 'Contact Us' button above and let us know the format that you need!


1. 'Separations with Fluorous Silica Gel and Related Materials' in Handbook of Fluorous Chemistry Gladysz, J. A.; Curran, D. P.; Horvath, I. T. Eds. Wiley-VCH, 2004,  pp101-155.

2. D. P. Curran, Synlett 2001, 1488-1496.

HPLC columns


FluoroFlash® HPLC columns are packed with a proprietary fluorous silica gel specifically designed for HPLC applications.  Under F-HPLC conditions, FluoroFlash® silica gel separates compounds primarily based on fluorine content while compound polarity plays a minor secondary role.  This allows for the separation of fluorous compounds based on size of the fluorous tag and is the basis of fluorous mixture synthesis (FMS) where mixtures are deconvoluted using F-HPLC (1-4).  FluoroFlash® HPLC columns are available in range of sizes from analytical to semi-preparative.  Please consult the F-HPLC application note for more details.


1. Luo, Z. Y.; Zhang, Q. S.; Oderaotoshi, Y.; Curran, D. P. Science, 2001, 291, 1766-1769.

2. Curran, D. P.; Furukawa, T. Organic Lett. 2002, 4, 2233-2235.

3. Zhang, W.; Luo, Z.; Chen, C. H.-T.; Curran, D. P. J. Am. Chem. Soc. 2002, 124, 10443-10450.

4. Jian, H.; Tour, J. M. J. Org. Chem. 2005, 70, 3396-3424.


FluoroFlash® HPLC Columns, 4.6 mm i.d., 50 mm length, 5 µm  
803-0505C Ea Inquire
FluoroFlash® HPLC Columns, 4.6 mm i.d., 150 mm length, 5 µm  
803-0510C Ea Inquire
Fluorous HPLC Columns, 10 mm I.d, 50 mm length  
803-1005C Ea Inquire
FluoroFlash® HPLC Columns, 10 mm i.d., 100 mm length  
803-1010C Ea Inquire
FluoroFlash® HPLC Columns, 20 mm i.d., 50 mm length, 5 µm  
803-2005C Ea Inquire
FluoroFlash® HPLC Columns, 20 mm i.d., 100 mm length, 5 µm  
803-2010C Ea Inquire
FluoroFlash® HPLC Columns, 20 mm i.d., 250 mm length  
803-2025C Ea Inquire