Fluorous salen-Co complex has been reported for the kinetic resolution of terminal epoxides. The fluorous version allows these reactions to be conducted under fluorous biphasic conditions providing a ready method for recovery and reuse of the catalyst (1,2). Alternatively, the ligand and metal complex can be removed using F-SPE. For optically pure versions of F034090, please contact FTI.
1. Cavazzini, M.; Quici, S.; Pozzi, G. Tetrahedron, 2002, 58, 3943-3949
2. Shepperson, I.; Cavazzini, M.; Pozzi, G.; Quici, S. J. Fluorine Chem. 2004, 125, 175-180.
|