Fluorous tin oxide has been reported as an effective catalyst for the selective sulfonylation of 1,2 diols (1), intermolecular transesterification (2), and microwave accelerated macrolactonization (3). When employed under microwave conditions, the fluorous tin oxide was found to provide better yields than other organic tin oxide or distannoxane species. In all cases, the tin residues were then removed in >99% by F-SPE.
1. Bucher, B.; Curran, D. P. Tetrahedron Lett. 2000, 41, 9617-9621.
2. Kesavan, S.; Su, Q.; Shao, J.; Porco, J. A., Jr.; Panek, J. S. Org. Lett. 2005, 7, 4435-4438.
3. Beeler, A. B.; Acquilano, D. E.; Su, Q.; Yan, F.; Roth, B. L.; Panek, J. S.; Porco, J. A., Jr. J. Comb. Chem. 2005, 7, 673-681.