Fluorous Metal Scavengers
Fluorous scavengers (1) are analogous to solid supported scavengers that are used to consume excess reagents in a variety of reactions. Fluorous scavengers have the advantage of solution phase kinetics, precise control of stoichiometry, and greater reactivity therefore requiring fewer equivalents. Both the scavenger and the scavenged products are then easily separated from the desired product by fluorous solid phase extraction.
1. For a general review on fluorous scavengers please see Lindsley, C. W.; Leister, W. H. “Fluorous Scavengers”, Handbook of Fluorous Chemistry, 2004, 236-246.