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Isatoic anhydride

Isocyanate

Oxybenzaldehyde   

Fluorous Metal Scavengers   

Scavengers - electrophilic

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Fluorous scavengers (1) are analogous to solid supported scavengers that are used to consume excess reagents in a variety of reactions.  Fluorous scavengers have the advantage of solution phase kinetics, precise control of stoichiometry, and greater reactivity therefore requiring fewer equivalents.  Both the scavenger and the scavenged products are then easily separated from the desired product by fluorous solid phase extraction. 

 

1. For a general review on fluorous scavengers please see Lindsley, C. W.; Leister, W. H. “Fluorous Scavengers”, Handbook of Fluorous Chemistry, 2004, 236-246.

 

Isatoic anhydride
 

 

Fluorous isatoic anhydride is a solution phase scavenger of nucleophiles such as amines and thiols and has been used in the solution phase parallel synthesis of urea, thiourea, and β-hydroxyamine analogs (1)

 

1. Zhang, W.; Chen, C. H.-T.; Nagashima, T. Tetrahedron Lett. 2003, 44, 2065-2068.

 

Rf NAME/CAS# PROPERTIES CATALOG# QTY PRICE
C8F17 1-[3-(Perfluorooctyl)propyl]-(1H-benzo[d][1,3] oxazine-2,4-dione  
C19H10F17NO3
F017028-0002 2g $97.00
    FW:  623.3 F017028-0010 10g $401.50
      F017028-0025 25g $850.00
      F017028-0100 100g $2,389.50
     
 

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