Fluorous Applications

• Small Molecule Synthesis
  • Library Synthesis & Fluorous Tagging
  • Scavengers & Reagents
  • Fluorous Mixture Synthesis
• Biomolecule Synthesis
  • Peptide Synthesis
  • Oligonucleotide Synthesis
  • Carbohydrate Synthesis
• Life Science Applications
  • Proteomics
  • Metabolomics
  • Microarraying and HTS

RELATED PRODUCTS

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Fluorous Metabolomics

Benefits of Fluorous Metabolomics

• Advance your research with cutting edge technology
• Reduce the complexity of your sample by fluorous enrichment
• Tailor the approach to enrich different subsets of peptides or small molecules
• Obtain high selectivity
• Overcome the limitations of traditional biotin-streptavidin methods
• Integrate fluorous techniques easily into your workflow

Fluorous techniques can simplify and streamline your peptide synthesis and purification whether you are making peptide libraries in small quantities or single therapeutic peptides in large quantity. The key to the purification is fluorous solid phase extraction (FSPE), a single general purification technique that is applicable over a wide range of peptides. Since FSPE only differentiates between fluorous tagged and non-tagged entities, an entire library of peptides can be purified using a single method. If you are making a single peptide the same method can be used to separate closely related peptides, such as deletion sequences, to provide an efficient and simple method by which to pre-purify a sample prior to final reverse phase HPLC resulting in greater recovery and efficiency.

Get Started with Fluorous Metabolomics

Fluorous Technologies Inc. can provide you with all the necessary reagents and FluoroFlash® silica gel used for metabolite tagging and enrichment. FluoroFlash® silica gel is available in convenient pipette form, in pre-packed micro LC format, or in loose bulk format for those who prefer to pack their own separation media. Please view our product offering, listed under Related Products to the left. You can read more about fluorous metabolomics by following the links in the For More Information section.

Selected References

• Go, E. P.; Uritboonthai, W.; Apon, J. V.; Trauger, S. A.; Nordstrom, A.; O'Maille, G.; Brittain, S. M.; Peters, E. C.; Siuzdak, G., J. Proteome Res. 2007; 6,(4), 1492-1499.
• Peters, E.; Brittain, S.; Ficarro, S.; Mason, D.; and Brock, A. Poster presented at HUPO 4th Annual World Congress, August 28–September 1, 2005, Munich