Many new products and applications;
Improved Product Descriptions and additional References
VISIT our On-Line Catalog Pages at any time to quickly get
to the product you need to succeed!
Application Notes (PDF)
Tags / Protecting groups
• Tagging with F-Boc-ON: fluorous analogue of the Boc-ON acid-labile N-protecting group/tag
• FluoMar: solution-phase Marshall resin equivalent™
• F-PMB-OH: fluorous propyl methoxy benzyl alcohol for tagging
• F-Cbz-OSu: fluorous benzyloxycarbonyloxy succinimide analogue; acid-labile N-protecting group/tag
• Using fluorous thiol as a tag
• Tagging with fluorous diisopropylsilane (TIPS analog)
Solution-phase Scavengers
• Nucleophile scavenging with fluorous isatoic anhydride
• Nucleophile scavenging with fluorous isocyanate
• Electrophile scavenging with fluorous thiol
Reagents and catalysts
• Fluorous Mitsunobu strategy for facile separation of byproducts
• F-PPh3: Using fluorous triphenylphosphine
• Fluorous palladium-phosphine catalyst for C-C bond formation
• Using the fluorous CDMT coupling reagent
• Using fluorous thiol to deprotect 2-nitrobenzenesulfonamides
• Using sulfonyl fluoride with phenols to form perfluorooctanesulfonates.
• Fluorous Mukaiyama's Reagent for activation of carboxylic acids to form esters, amides, and lactones.
• F-Sn=O: Selective sulfonylation of 1,2-diols using tin oxide as a catalyst
Sorbents - F-SPE Cartridges & F-HPLC
• F-SPE Cartridges and Frequently Asked Questions on F-SPE
• Fluorous HPLC
Sorbents - Parallel & High-Throughput F-SPE
Life Science Applications
Presentations (PDF)
The following
pdf-files were created from powerpoint presentations, so they're
fairly large. Please give your browser sufficient time for download.
• Presentations from the FTI CD given out at the ISoFT'07; Yokohama-Kamakura, Japan
- Fluorous 2007 Overview
- Fluorous Peptide Chemistry
- Fluorous Small Molecule Chemistry
- Fluorous Immobilization for Microarray Formation
• Improvements in the Synthesis and Purification of Small Molecule Libraries
Dr. Stefan Werner, Pitt CMLD - Drug Discovery Chemistry 2007 CHI, La Jolla, CA Presentation
• New Fluorous Separation Techniques for Parallel and High-Throughput Synthesis
Dr. Wei Zhang, 2007 - Poster, Combichem Gordon Research Conference
Fluorous Multicomponent Reactions for Making Drug-like Molecules
Dr. Wei Zhang, 2007 - Poster, Combichem Gordon Research Conference
• Fluorous Chemistry - A New Technology Platform
Dr. Wei Zhang, 2007 - 1.8MB
• Fluorous Enhanced Combinatorial Synthesis
Dr. Wei Zhang - 1,000KB
• Fluorous Techniques for High-Throughput Synthesis
Dr. Dennis Curran, 2006 - 1.5MB
• High-Throughput Organic Synthesis using Fluorous Technology
Yimin Lu , 2006 ACS San Francisco, CA Presentation - 330KB
• Fluorous Benzaldehydes for Diversity-Oriented Synthesis
Dr. Wei Zhang, 2005 ACS San Diego Poster - 1.5MB
• Development of New Fluorous Scavenging and Coupling Reagents
Dr. Wei Zhang, 2005 ACS San Diego Poster - 1.2MB
• Fluorous-enhanced
chemical transformations in drug discovery synthesis
Dr. Marvin Yu, Director- 751
KB
•
Combining Fluorous and Microwave Technologies for High-Speed Reaction and Separations
Dr. Wei Zhang, 2004 ACS Symposium - 1,210 KB
•
Emerging fluorous applications in process chemistry
Dr. Marvin Yu, 2004 ACS Showcase - 631
KB
•
Emerging fluorous applications in biopolymer synthesis and purification
Dr. Marvin Yu, 2004 ACS Showcase - 887
KB
•
Recent advancements in fluorous chemistry
Dr. Philip Yeske, 2004 ACS Showcase - 364 KB
Sigma-Aldrich Fluorous Cheminar and ChemFiles
Information Materials (PDF)
• FTI's Technology Primer
• Reviews, Publications, Patents (Updated April 2007
Frequently Asked Questions
For your convenience, some of the questions most asked by our customers and web site visitors are listed in a separate web page which can be accessed by clicking here. You may submit other questions through our feedback section or by emailing us at contact-fti@fluorous.com.
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