Fluorous Applications

BioMolecule Synthesis

Benefits of Fluorous Biomolecule Synthesis

  • Complement traditional solid phase synthesis with strategic separations
  • Easily add a powerful, robust purification method into your existing workflow
  • Access longer biomolecules that are problematic with other methods
  • Reduce the number of steps needed to synthesize and immobilize a biomolecule

Fluorous chemistry represents a novel orthogonal phase that can be used in the synthesis and purification of peptides, oligonucleotides, and carbohydrates. Fluorous techniques for biomolecule synthesis include:

  • Solid- or solution-phase synthesis with terminal fluorous tagging
  • Solid- or solution-phase synthesis with fluorous capping
  • Solution- phase synthesis on a fluorous support
  • Solution-phase synthesis using fluorous coupling reagents

In all cases, the fluorous compounds can be separated from the non-fluorous compounds using either fluorous solid phase extraction (FSPE) or fluorous liquid-liquid extraction (FLLE). Fluorous Technologies Inc. can provide you with the right reagents and sorbents to meet all your biomolecule synthesis and purification needs.

Please click on the application pages to learn more about fluorous techniques for biomolecule synthesis.