Fluorous Technologies Inc. - Chemistry Compatibility Chart

Chemistry Compatibility Chart

Functional Group	Scaffold	Reactant	Fluorous Scavengers	Fluorous Reagents
Amide	Acid chloride	Amine or Aniline	F-Isocyanate F-Isatoic anhydride F-Alkyl halide
	Amine	Acid chloride	F-Amine F-Thiol
	Amine	Carboxylic acid		F-DCC F-HOBT F-Pyridinium salt
	Aniline	Acid chloride	F-Amine F-Thiol
	Aniline	Carboxylic acid		F-DCC F-HOBT F-Pyridinium salt
	Carboxylic acid	Amine	F-Isocyanate F-Isatoic anhydride F-Alkyl halide
		Aniline	F-Isocyanate F-Isatoic anhydride F-Alkyl halide
Amine	Aldehyde	Amine or Aniline	F-Isocyanate F-Isatoic anhydride F-Alkyl halide
		Aniline
	Amine	Aldehyde	F-Amine
		Aryl halide	F-Amine F-Thiol	F-Benzophenone Imine
		Alkyl halide	F-Amine F-Phosphine	F-DIAD F-TPP (Mitsunobu with imide)
	Aniline	Aldehyde	F-Amine
	Ketone	Amine or Aniline	F-Isocyanate F-Isatoic anhydride F-Alkyl halide